| Gospodarze | Goście | Data meczu |
| Asseco Resovia Rzeszów | Stal Nysa | 2022-01-22 20:30 |
| Stal Nysa | Trefl Gdańsk | 2022-01-28 20:30 |
| Ślepsk Malow Suwałki | Stal Nysa | 2022-02-05 17:30 |
| Stal Nysa | Aluron CMC Warta Zawiercie | 2022-02-12 17:30 |
| GKS Katowice | Stal Nysa | 2022-02-19 17:30 |
| Stal Nysa | Indykpol AZS Olsztyn | 2022-03-05 17:30 |
| Cuprum Lubin | Stal Nysa | 2022-03-12 17:30 |
| Stal Nysa | Cerrad Enea Czarni Radom | 2022-03-19 17:30 |
| Stal Nysa | LUK Lublin | 2022-03-26 17:30 |
| Projekt Warszawa | Stal Nysa | 2022-04-02 17:30 |
